Guy A Rutter Selected Research

zinc-binding protein (zinc binding protein)

11/2022	Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine-induced cell death.
1/2018	Sensors for measuring subcellular zinc pools.
1/2017	The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.
12/2016	Zinc and diabetes.
8/2015	The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.
8/2015	The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
1/2010	Think zinc: New roles for zinc in the control of insulin secretion.
9/2009	Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

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Guy A Rutter Research Topics

Disease

55	Type 2 Diabetes Mellitus (MODY) 11/2022 - 08/2002
13	Obesity 01/2021 - 07/2006
10	Insulin Resistance 01/2022 - 06/2008
7	Diabetes Mellitus 12/2018 - 10/2003
6	Hypoxia (Hypoxemia) 11/2022 - 01/2010
6	Insulinoma 01/2022 - 04/2003
6	Hyperglycemia 01/2022 - 04/2005
6	Body Weight (Weight, Body) 01/2022 - 09/2009
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2018 - 06/2008
5	Neoplasms (Cancer) 01/2018 - 06/2010
5	Hypoglycemia (Reactive Hypoglycemia) 01/2016 - 06/2005
4	Weight Loss (Weight Reduction) 12/2022 - 01/2018
4	Glucose Intolerance 01/2022 - 12/2014
4	Pancreatitis 01/2016 - 03/2008
3	Inflammation (Inflammations) 11/2022 - 01/2020
3	Weight Gain 01/2021 - 06/2010
3	Nausea 01/2018 - 12/2015
2	Infections 01/2020 - 03/2004
2	Pulmonary Hypertension 01/2018 - 08/2015
2	Wolfram Syndrome (Syndrome, Wolfram) 02/2015 - 01/2008
2	Neuroblastoma 02/2015 - 01/2008
2	Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal) 11/2014 - 06/2010
2	Hyperinsulinism (Hyperinsulinemia) 07/2012 - 09/2007
1	Hyperhomocysteinemia 01/2022
1	Homocystinuria 01/2022
1	Peripheral Nerve Injuries 11/2021
1	Body Weight Changes 08/2020
1	COVID-19 01/2020
1	Abdominal Obesity 01/2020
1	Phototoxic Dermatitis (Phototoxicity) 12/2019
1	Hypertrophy 01/2019
1	Arteriosclerosis 07/2018
1	Dyslipidemias (Dyslipidemia) 01/2018
1	Cushing Syndrome 01/2018
1	AIDS-Related Complex (ARC) 01/2018
1	Nervous System Diseases (Neurological Disorders) 01/2018
1	Hyperplasia 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018

Drug/Important Bio-Agent (IBA)

35	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2002
25	Insulin (Novolin)FDA Link 01/2021 - 08/2002
8	zinc-binding protein (zinc binding protein)IBA 11/2022 - 09/2009
8	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2021 - 11/2014
8	Proteins (Proteins, Gene)FDA Link 03/2018 - 03/2004
7	Hormones (Hormone)IBA 01/2018 - 07/2006
6	AMP-Activated Protein KinasesIBA 01/2022 - 06/2004
6	Phosphotransferases (Kinase)IBA 01/2018 - 06/2010
5	ZincIBA 11/2022 - 08/2015
5	Glucagon-Like Peptide-1 ReceptorIBA 01/2021 - 01/2018
5	Glucagon (Glukagon)FDA Link 12/2018 - 06/2005
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2003
3	Hypoglycemic Agents (Hypoglycemics)IBA 11/2022 - 09/2007
3	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2016
3	Adenosine Triphosphate (ATP)IBA 10/2020 - 06/2008
3	Messenger RNA (mRNA)IBA 08/2020 - 08/2014
3	Proglucagon (Glucagon Precursors)IBA 01/2016 - 11/2014
3	Metformin (Glucophage)FDA LinkGeneric 05/2015 - 06/2004
3	Protein Kinases (Protein Kinase)IBA 11/2014 - 06/2010
3	Protein Isoforms (Isoforms)IBA 02/2011 - 04/2005
2	Blood Glucose (Blood Sugar)IBA 11/2022 - 01/2021
2	Sirtuin 3IBA 01/2022 - 01/2021
2	Biological ProductsIBA 11/2021 - 11/2021
2	LipidsIBA 10/2020 - 11/2006
2	GlucocorticoidsIBA 01/2020 - 01/2018
2	Zinc Transporter 8IBA 11/2019 - 08/2014
2	IncretinsIBA 07/2018 - 12/2015
2	Exenatide (Byetta)FDA Link 03/2018 - 01/2014
2	Pharmaceutical PreparationsIBA 08/2015 - 06/2004
2	Adenosine Triphosphatases (ATPase)IBA 02/2015 - 01/2008
2	Pyruvic Acid (Pyruvate)IBA 07/2012 - 09/2007
2	(L)-Isomer Glucose (L-Glucose)IBA 04/2006 - 04/2005
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2006 - 04/2003
2	enhanced green fluorescent proteinIBA 04/2006 - 04/2003
1	semaglutideIBA 11/2022
1	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 11/2022
1	CytokinesIBA 11/2022
1	GTP-Binding Proteins (G-Protein)IBA 11/2022
1	CystathionineIBA 01/2022
1	HomocysteineIBA 01/2022
1	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 01/2022
1	CateninsIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	ChromatinIBA 01/2021
1	ArrestinsIBA 01/2021
1	C-PeptideIBA 01/2021
1	HDL CholesterolIBA 01/2021
1	Serotonin (5 Hydroxytryptamine)IBA 01/2021
1	LigandsIBA 11/2020
1	Carrier Proteins (Binding Protein)IBA 10/2020
1	ProinsulinIBA 10/2020
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2020
1	Polysaccharides (Glycans)IBA 01/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	Serine (L-Serine)FDA Link 10/2018
1	ClathrinIBA 03/2018
1	Sorting NexinsIBA 03/2018
1	Tamoxifen FDA LinkGeneric 01/2017

Therapy/Procedure

7	Therapeutics 11/2021 - 09/2015
4	Bariatric Surgery 12/2022 - 01/2020
1	Anesthesia 12/2019
1	Lasers (Laser) 01/2018